Fatcel: Difference between revisions

*The Animal Fats<ref name=":1" /> and Plant Oils<ref>https://slimemoldtimemold.com/2021/08/18/a-chemical-hunger-interlude-e-bad-seeds/</ref> Theory can also be thrown out, and that even though dietary fat and carbohydrates can make people gain weight ins the short one (low food satiety), they do not make people healthy people fatter in the long run. Keto, Low-Fat and Low-Glycemic Diets are all useless when compared to Paleo, Vegan, or even "western" diets, when adjusted to long-term boomerang effects. Analysis<ref>https://www.healthline.com/nutrition/23-studies-on-low-carb-and-low-fat-diets</ref> noted that even if low-carb diets work 2-3x as effective at weight loss in certain conditions, and can improve triglycerides and cholesterol levels, the '''failure''' rate of both low-carb and low-fat diets are on average '''22%'''. Another review<ref>https://pubmed.ncbi.nlm.nih.gov/33317019/</ref> noted that a low-carb diet also has the side effect of lowering lean mass (muscles), thus it can be said that ketogenic diet is synonymous to a starvation diet.

* "Addictive Food" and "Liquid Food"<ref>https://slimemoldtimemold.com/2021/07/23/a-chemical-hunger-interlude-b-the-nutrient-sludge-diet/</ref> Theory can be thrown out as fat people will always eat more, even when controlling for ease of food delivery and food tastelessness. In general, people find it harder to predict the energy density of bigger portions<ref>http://www.brianwansink.com/qa-blogus/why-do-overweight-people-underestimate-how-much-they-eat</ref>. Also, only overweight people who attempts a diet can predict calorie more accurately than other healthier and/or non-dieting populations<ref>https://mhrc.info.yorku.ca/files/2016/09/September-2016-Kuk.pdf</ref>. This implies that healthy individuals have no incentive to care about dieting.

*One factor not included in the blog is the idea that people who are overweight are less physically active. As noted in later paragraphs, physical activity and metabolism is also genetically biased.

*Genetics is by far the other factor not denied by the blog, but he had presented<ref>https://slimemoldtimemold.com/2021/09/20/a-chemical-hunger-interlude-f-demographics/</ref> data that controls for race, where even when blacks are statistically more likely to be fatter than whites, those that live in certain areas are more likely to be fatter, implying that there are inter-ethnic genetic difference that is consistent between races. It also controlled for income (a stand-in of Socio-Economic Status and often [[Life history]]) and that the effects of poverty and obesity disappears as early as 1990 (however US grain subsidies started in 1995 so the argument is not as strong), and it did not provide a reason why low income is correlated to obesity.

*Obesity only started to be an issue in less than a century ago

*Non-industrialized nations are not effected by obesity, even if their diets are matching western diet

*Altitude and watershed exposure are a main predictor in obesity

*Obesity is a universal pattern for zoo animals, lab animals and wild animals, industrial locals and long-term migrants alike

One core theory suggested by these findings is that humans have a "Lipostat"<ref name=":1" /> (AKA "Ponderostat") that regulates human fat storage. This is done through Ghrelin (hunger hormone) and Leptin (satiety hormone). Obesity is caused by leptin malfunction, can be cured neurologically (psychiatric medication), or by "blowing the heater" (gastric bypass). But this merely explains how it leads to obesity, but not what caused it.

A major claim by the article is that endocrine disruptors and psychiatric contaminants are to blame, for example Lithium<ref>https://slimemoldtimemold.com/2021/08/02/a-chemical-hunger-part-vii-lithium/</ref> and PFAS<ref>https://slimemoldtimemold.com/2021/07/26/a-chemical-hunger-part-vi-pfas/</ref>. There is a relationship between Obesity population, and the same population having Anorexia or Bulimia<ref>https://slimemoldtimemold.com/2021/08/21/a-chemical-hunger-part-viii-paradoxical-reactions/</ref>. The author is hesitant on more serious [[Femoid]]-adjacent chemicals e.g. Oral Contraception AKA Birth Control AKA "The Pill", even though the readers are routinely requesting him to address such issues.

=== Alternative Hypothesis: "It is purely genetic" ===

Recent genetic studies<ref><nowiki>https://doi.org/10.1002/oby.23116</nowiki></ref> noted that the major cause of obesity comes from genes that affect brain development, endocrine system and metabolism. When comparing the genetics of Whites and East Asians, there are at least 25 gene variants<ref>https://doi.org<nowiki/>/10.3389/fgene.2020.575049</ref> that can be identified between these two ethnicities, however the other 31 Asian obesity gene variations cannot be found in the White obesity gene variants of more than 750.The discrepancy in intra-ethnic gene count could be caused by environmental differences, and the propensity for westerners to over-report gene variants with no research control on environment whilst Asians are more culturally homogenous. Newer research has mechanisms<ref>https://doi.org/10.1093/bmb/ldx022</ref> to counteract such issues.

Note: Genetic risk of obesity and BMI is independent<ref>https://cmcoem.info/pdf/curso/genetica_de_la_obesidad/geneticsofobesitylancet.pdf</ref> of birth weight and waist-to-hip ratio (alternative indicators of [[Life history]] or body [[Feminization]])

=== Alternative Hypothesis: "You cannot blame genetics" ===

Harvard<ref>https://www.hsph.harvard.edu/obesity-prevention-source/obesity-causes/genes-and-obesity/</ref> popularized the idea that "physical activity outweighs the FTO gene", where they claim that genetics can only be 3% effective as a cause of obesity. However there are other issues with this line of reasoning, that physical activity and metabolism are also genetically driven(Gene expression<ref>https://doi.org<nowiki/>/10.1186/s12966-020-01077-5</ref>, Twin Studies<ref><nowiki>https://doi.org/10.1371/journal.pone.0000022</nowiki></ref>), and that there are triple-digits worth of genes that are in relation to obesity<ref>https://www.ncbi.nlm.nih.gov/pubmed/31564431</ref>.

=="Fatcel is volcel" argument==

The "fatcel is volcel" argument states that you can’t call yourself [[involuntary celibate]] if you haven’t made an effort to exercise and thereby make yourself more appealing, or lost enough pounds to be at a healthy weight. Fatcels are in fact hated by [[truecels]].