Even though the vast majority is deleterious, some mutations are good. An example is the ACTN3 gene giving West African sprinters faster fast-twitch muscle fibers and therefore a faster sprint spreed.
Ugly mutations of physical appearance do rarely warrant reasons for concern as ugliness is only weakly related with disease. However, various genetic diseases, functional and
intellectual impairment do warrant concern and reduce overall population viability if maintained in the gene pool (dysgenics). Fortunately, we will possibly be able to remove such diseases via gene editing in near future.<ref>https://www.npr.org/sections/health-shots/2017/08/02/540975224/scientists-precisely-edit-dna-in-human-embryos-to-fix-a-disease-gene?t=1577487765548</ref>
Even though some mutations are beneficial, the news media only focus on deleterious mutations, presumably because bad news is more attention grabbing.<ref>https://www.adweek.com/digital/bad-news-negative-headlines-get-much-more-attention/</ref> People are also hardwired to bully mutants to increase their own [[reproductive success]].<ref>https://journals.sagepub.com/doi/abs/10.1177/0886260515593546</ref><ref>https://www.researchgate.net/publication/301670151_Adolescent_Bullying_in_Schools_An_Evolutionary_Perspective</ref>