Asperger's syndrome: Difference between revisions

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The complementary imprinted brain theory puts psychotic spectrum disorders (such as schizophrenia) on the opposite end of a spectrum from ASD, purportedly resulting from a conflict in the genomic imprinting between paternal and maternal genes, with an extreme genomic imprinting in favor of paternal genes being associated with ASD<ref>https://www.psychologytoday.com/intl/blog/the-imprinted-brain/201506/testing-the-extreme-female-brain-theory-psychosis</ref>. This also corresponds with sex differences in empathizing vs systemizing <ref>https://www.pnas.org/content/115/48/12152?fbclid=IwAR0ngaYIo88A77EKpALefnsr54ZZpPWGbatCYNPBcC84HgcDGmsZ2c6VgB4</ref>, which find females are generally higher in empathizing and males highest in systemizing, with autistic individuals of both sexes typically displaying a more masculinized behavioral phenotype. These developmental theories are not necessarily mutually exclusive with the theories of ASD that attribute the etiology of the disorder to greater mutational load.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895441/</ref>
The complementary imprinted brain theory puts psychotic spectrum disorders (such as schizophrenia) on the opposite end of a spectrum from ASD, purportedly resulting from a conflict in the genomic imprinting between paternal and maternal genes, with an extreme genomic imprinting in favor of paternal genes being associated with ASD<ref>https://www.psychologytoday.com/intl/blog/the-imprinted-brain/201506/testing-the-extreme-female-brain-theory-psychosis</ref>. This also corresponds with sex differences in empathizing vs systemizing <ref>https://www.pnas.org/content/115/48/12152?fbclid=IwAR0ngaYIo88A77EKpALefnsr54ZZpPWGbatCYNPBcC84HgcDGmsZ2c6VgB4</ref>, which find females are generally higher in empathizing and males highest in systemizing, with autistic individuals of both sexes typically displaying a more masculinized behavioral phenotype. These developmental theories are not necessarily mutually exclusive with the theories of ASD that attribute the etiology of the disorder to greater mutational load.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895441/</ref>


It has also been proposed <ref>https://www.academia.edu/36525083/ADHD_Autism_and_Psychopathy_as_Life_Strategies_The_Role_of_Risk_Tolerance_on_Evolutionary_Fitness</ref> that ASD represents a 'failed' male evolutionary mating strategy adaption, whereas the disorders that are similar in their etiology and pathology in some respects to autism such as Attention Deficit Hyperactivity Disorder(ADHD) and Anti-Social Personality Disorder (ASPD, commonly known as 'psychopathy') represent more beneficial adaptions in general <ref>https://www.reddit.com/r/BlackPillScience/comments/bnnr6r/teenage_boys_with_adhd_are_much_more_successful/</ref>, particularly the "dark triad" personality traits associated with ASPD, which are associated with a lower arousal threshold (less or no fear, desire for extreme stimulation, very low inhibition) and such are probably not 'trainable' but rather innate, contra [[r/TRP]].<ref> https://www.researchgate.net/publication/273809664_The_Dark_Triad_personality_Attractiveness_to_women</ref>
Theories based on evolutionary psychology have proposed <ref>https://www.academia.edu/36525083/ADHD_Autism_and_Psychopathy_as_Life_Strategies_The_Role_of_Risk_Tolerance_on_Evolutionary_Fitness</ref> that ASD represents a 'failed' male evolutionary mating strategy adaption, with the disorders that are somewhat similar in their etiology and pathology to autism such as Attention Deficit Hyperactivity Disorder(ADHD) and Anti-Social Personality Disorder (ASPD, commonly known as 'psychopathy') likely represent more beneficial adaptions in general.<ref>https://www.reddit.com/r/BlackPillScience/comments/bnnr6r/teenage_boys_with_adhd_are_much_more_successful/</ref>
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Psychopathic traits include a lower arousal threshold (less or no fear, desire for extreme stimulation, very low inhibition) and it is argued these improve mating success in men, whereas autism clearly is detrimental to mating success.<ref>https://link.springer.com/article/10.1007/s40806-019-00213-0</ref>


==Advanced parental age and mutational load==
==Advanced parental age and mutational load==

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