6,353
edits
Line 17: | Line 17: | ||
Serum testosterone levels are far less clinically relevant than levels of unbound (free) testosterone, so what is important to establish a real decline in T levels would be to prove that levels of free-testosterone are falling. | Serum testosterone levels are far less clinically relevant than levels of unbound (free) testosterone, so what is important to establish a real decline in T levels would be to prove that levels of free-testosterone are falling. | ||
Many men have high serum T levels because their level of SHBG is high, which means most of the T they produce is effectively useless. Intakes of dietary protein in wealthy Western countries are also generally higher than in developing countries,<ref>https://www.wri.org/data/people-are-eating-more-protein-they-need-especially-wealthy-regions</ref> which together with dietary fibre intake also being negatively correlated with country level economic development,<ref>https://www.robertbarrington.net/fibre-intake-various-countries/</ref> generally results in lower levels of SHBG in the bloodstream, which would again lead to the bodies of Western individuals being generally more sensitive to the effects of T | Many men have high serum T levels because their level of SHBG is high, which means most of the T they produce is effectively useless. Intakes of dietary protein in wealthy Western countries are also generally higher than in developing countries,<ref>https://www.wri.org/data/people-are-eating-more-protein-they-need-especially-wealthy-regions</ref> which together with dietary fibre intake also being negatively correlated with country level economic development,<ref>https://www.robertbarrington.net/fibre-intake-various-countries/</ref> generally results in lower levels of SHBG in the bloodstream, which would again lead to the bodies of Western individuals being generally more sensitive to the effects of T compared to people in developing countries. <ref>https://academic.oup.com/jcem/article/85/1/293/2854619?login=true</ref> | ||
Another flaw with many of these studies is that they do not control for the fact that smoking has massively decreased in Western countries,<ref>https://ncci.canceraustralia.gov.au/prevention/smoking-prevelance/smoking-prevalence-adults</ref> with cigarette consumption peaking in the 1950s and falling to low levels in the modern era.<ref>https://ourworldindata.org/smoking</ref> | Another flaw with many of these studies is that they do not control for the fact that smoking has massively decreased in Western countries,<ref>https://ncci.canceraustralia.gov.au/prevention/smoking-prevelance/smoking-prevalence-adults</ref> with cigarette consumption peaking in the 1950s and falling to low levels in the modern era.<ref>https://ourworldindata.org/smoking</ref> |
edits