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Testosterone: Difference between revisions
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If this finding proves robust, this reduction in SHBG would result in less negative feedback being exerted on men's hypothalamic-pituitary-gonadal axis (HPG axis), which would lead to the body downregulating T production as it essentially needs less to produce the desired effects. Meaning the secular decrease in T wouldn't be particularly relevant in driving any practical differences in population level masculinization. | If this finding proves robust, this reduction in SHBG would result in less negative feedback being exerted on men's hypothalamic-pituitary-gonadal axis (HPG axis), which would lead to the body downregulating T production as it essentially needs less to produce the desired effects. Meaning the secular decrease in T wouldn't be particularly relevant in driving any practical differences in population level masculinization. | ||
One should take studies on the effects of testosterone on driving certain psychological changes should be taken with a grain of salt, as many studies that examine the effects of testosterone (and other hormones) on psychology are deeply flawed. A large amount of these kinds of studies do not take these inter-hormone interactions into account, do not use particularly reliable measures of testosterone, have low sample sizes, do not take into account interindividual differences in sensitivity to androgens, and do not take into account the effects prenatal and pubertal 'priming' may have on shaping the body's response to testosterone in adulthood. Adult T-levels are also substantially affected by lifestyle factors <ref>https://academic.oup.com/jcem/article/92/2/549/2566787?login=true</ref><ref>https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.1019.6064&rep=rep1&type=pdf</ref> such as age, smoking, body fat percentage and general health, which is likely another confounding factor in such studies. | One should take studies on the effects of testosterone on driving certain psychological changes should be taken with a grain of salt, as many studies that examine the effects of testosterone (and other hormones) on psychology are deeply flawed. A large amount of these kinds of studies do not take these inter-hormone interactions into account, do not use particularly reliable measures of testosterone, have low sample sizes, do not take into account interindividual differences in sensitivity to androgens, and do not take into account the effects prenatal and pubertal 'priming' may have on shaping the body's response to testosterone in adulthood. Adult T-levels are also substantially affected by lifestyle factors<ref>https://academic.oup.com/jcem/article/92/2/549/2566787?login=true</ref><ref>https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.1019.6064&rep=rep1&type=pdf</ref> such as age, smoking, body fat percentage and general health, which is likely another confounding factor in such studies. | ||
==T and social dominance== | ==T and social dominance== | ||