Asperger's Syndrome

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Asperger's Syndrome is an Autism Spectrum "Disorder" (ASD) that can contribute to someones inceldom. The diagnosis was previously distinct from ASD in the United States, but was subsumed into the broader diagnosis of ASD in the DSM-5 manual released by the American Psychiatric Association (APA) in 2013.[1] It is still recognized in the ICD-11 maintained by the World Health Organization as a subset of autism.[2] The diagnosis of Asperger's syndrome is/was dependent on the subject meeting the criteria for a certain level of autistic symptoms such as social deficits and obsessive interests while having an IQ in the normal range or higher and not experiencing any developmental delay in language acquisition.

The condition is named after Hans Asperger, an Austrian paediatrician who first described the disorder in a medical context, dubbing the condition "autistic psychopathy"(in German the word "psychopathische" was often used to refer to any type of mental illness).[3][4] Asperger is a highly controversial figure due to revelations he contributed to the Nazi Aktion T4 'euthanasia' program,[5] and recent discovery of his role in the T4 program may have also been a factor in the redefinition of the disorder by the APA.

People with Asperger's often experience difficulty socializing and blending in with normies, largely due to being bad with emotional recognition and expression, the condition sometimes being co-morbid or conflated with Prosopagnosia (face-blindness).[6]

On the other hand, they are often exceptionally good at recognizing patterns and investigating certain topics with intense focus. People with Asperger's are also vulnerable targets of pick up artists who scam them into buying into their ineffective programs, with Aspies often being subject to the "Attraction ambiguity problem".

Free Lesson for Aspies[edit | edit source]

A guide to female cues for our wonderful, irreplaceable brethren with Aspergers...


full
Interested in you.


full
Not interested in you.

Autism and inceldom[edit | edit source]

69% of high functioning autistic adolescents want relationships, but almost none succeed[edit | edit source]

The parents of 190 adolescents with high and low functioning autism were surveyed to evaluate the adolescents' perspectives around sexuality.[7][8]

The adolescents upon whom parents were reporting were predominantly Caucasian (89.3 %) males (86.8 %) with a median age of 14 years (M = 14.51, SD = 1.96).

Findings were:

  • 69.2% of adolescents with high functioning autism expressed desire for a dating relationship.
  • 73.1% with high functioning autism expressed attraction to someone of the opposite sex, and 10.0% to the same sex.
  • However, only 7.7% of this high functioning autistic cohort reported having had a relationship with someone of the opposite sex, and 1.5% with someone of the same sex.
  • Only 1.5% of the group had sex.

Overall this group showed a normal amount of desire for sexual relationships, but a disproportionately low capacity to achieve them.

44.6% of high functioning adult autistic men remain virgins, despite high sex/relationship drive[edit | edit source]

A group of high functioning autistic men and women were evaluated and compared with healthy controls to assess their sexual and relationship desires and success/failure to achieve those desires.[9]

44.6% of autistic men were found to still virgins among a sample with the average age being 35.7 years. (Note: This figure is likely understating the number of ASD men who are incel, as there are a disproportionately higher number of homosexual/biseuxal men with ASD compared to NTs. The researchers lumped these into a single group.) This is also despite men with ASD reporting having higher levels of sexual desire and masturbating more frequently then NT men.

Autistic men were found to masturbate more and have a greater desire for a relationship than normal neurotypical (NT) men. However, only 16% of autistic men were in a relationship while 82% of NT men were in a relationship. NT men were 5x more likely to be in a relationship than their autistic counterparts.

Autism did not so greatly reduce women's ability to find relationships with men, as 46% of women were able to have relationships, while only 16% of men were. It was also noted that Female ASD individuals were significantly younger at time of first sexual intercourse (then males with ASD).

This is possibly due to the fact that autism reduces an individual's capacity for emotional interaction, but normal men crave emotional interaction less than normal women, so this will disproportionately impair an autistic man's attempts to find a relationship vs. an autistic woman's. Another possible explanation is that autists, due to their atypical behavior and emotional recognition deficits, find it difficult to navigate complex social dominance hierarchies, and are also socially excluded because of these atypical behaviors.[10]

Autistic men were also burdened with a dramatically greater number of paraphilias which are considered "socially taboo". These paraphilias which appear to be part of their disease state can only be imagined to make their difficulties in finding sexual and romantic success more difficult.

Quotes:

  • Male ASD participants reported more frequent masturbation than male healthy controls (HCs) (P<0.01).
  • ASD men reported a greater sexual desire for sexual intercourse than their HC counterparts (P<0.05, Table III).
  • Of the individuals with ASD, significantly more women (n=18; 46.2%) than men (n=9; 16.1%) were currently in a relationship

Autism and suicide[edit | edit source]

Numerous studies show the harms of autism are deep and painful to those who must bear them. Autistic individuals are subjected to at least 4-5x as much bullying as normal children. Autistic children report 28x more suicidal ideation or attempts compared to normal children.[11] Autistic adults report nearly 10 times as many suicidal thoughts.[12] Overall, people with autism are 7.53 times more likely to die by suicide, those with high-functioning autism having a greater risk of committing suicide than the low functioning, being 9.36 times more likely to commit suicide.[13]

A clinical cohort study of adults recently diagnosed with Asperger's Syndrome (N = 374, 256 men, 116 women) in 2014 found a much greater prevalence of suicidal ideation and attempts/plans for suicide among adults with Asperger's as compared to the general population. Specifically adults with Asperger’s syndrome are much more likely to report lifetime experience of suicidal ideation than were individuals from a general UK population sample (odds ratio 9.6), and 35% of respondents reported having actually planned their suicide.[14]

Neurodiversity vs autistic pathology[edit | edit source]

There is debate in the autistic community as to whether or not high-functioning autism in particular should be treated as a health problem or not. The "neurodivergent" or "neurodiversity" crowd argue the label is stigmatizing, or they imply autism is good/neutral. Those opposed to the "neurodivergent" and "neurodiversity" movements claim that these movements downplay behavioral and social issues often found in those diagnosed with Autism Spectrum Disorders.

Extreme male brain theory[edit | edit source]

A major controversial theory of the etiology (cause) of ASD is known as the extreme male brain theory. The theory first proposed by the world famous autism researcher from the University of Cambridge, Simon Baron-Cohen, states that the major cause of ASD is excessive exposure to androgens (male sex hormones) during prenatal development. Baron-Cohen does not claim that persons with ASD are more 'masculine' then neuro-typicals, a point often lost on laymen. Baron-Cohen merely asserts that this 'extreme' masculinity takes form in a deficit of empathy in ASD individuals, as well as an increase in their mental tendency to attempt to systemise information they receive from the external environment, which a major cause of the obsessional interests and social deficits displayed by those with the disorder. The theory is supported by analysis on the amniotic fluid of children who were later diagnosed with ASD, which found evidence of elevated androgens (androstenedione and testosterone) in the placental fluid.[15] However the relationship between these factors is likely complex; as later studies have also found evidence of elevated levels of estrogens in the pre-natal environment of those later diagnosed with autism[16]. This is likely partially due to the activity of the enzyme aromatase in the placenta, converting some of the androgens to estrogens, and there is animal evidence that pre-natal estrogens can have a "paradoxical" masculinizing effect in the right context.

The complementary imprinted brain theory puts psychotic spectrum disorders (such as schizophrenia) on the opposite end of a spectrum from ASD, purportedly resulting from a conflict in the genomic imprinting between paternal and maternal genes, with an extreme genomic imprinting in favor of paternal genes being associated with ASD.[17] This also corresponds with sex differences in empathizing vs systemizing,[18] which find females are generally higher in empathizing and males highest in systemizing, with autistic individuals of both sexes typically displaying a more masculinized behavioral phenotype. These developmental theories are not necessarily mutually exclusive with the theories of ASD that attribute the etiology of the disorder to greater mutational load.[19]

Advanced parental age and mutational load[edit | edit source]

There is some evidence that increasing deleterious mutational load in the population, mediated by advanced paternal age and also possibly by reductions in natural selection due to industrialization and modern medicine, is contributing to the increase in global autism diagnoses,[20] that may not be fully explicable by the broadening of the diagnostic criteria of autism or increased awareness of the issue.

Iossifov et al. (2015) found that 30% of cases of autism in simplex families (where only one immediate family member has the condition) arises from de novo (novel) mutations, often transmitted from the mother.[21][22] Taylor et al. found that simplex cases of autism were typically more problematic as compared to multiplex cases (multiple family members affected).[23] Advanced parental age at birth also heightens the risk of ASD in offspring, with a possible mediating role of greater paternal age increasing the incidence of de novo mutations leading to ASD in offspring.[24] Some researchers have claimed that the lessened prevalence of autism in women, rather than being explicable by the extreme male brain theory, may be due to an increased mutational load being required to contribute to the etiology of the condition in females.[25] This also implies that females who have the condition may exhibit stronger symptoms due to carrying more deleterious mutations than males with the condition. However, it is also claimed that the lesser female prevalence of the disorder may be due to higher-functioning female autists being more effective at 'masking' the socially disruptive symptoms of the condition.[26]

Evolutionary theories of autism[edit | edit source]

Theories based on evolutionary psychology have proposed [27] that ASD represents a 'failed' male evolutionary mating strategy adaption, with the disorders that are somewhat similar in their etiology and pathology to autism such as Attention Deficit Hyperactivity Disorder(ADHD) and Anti-Social Personality Disorder (ASPD, commonly known as 'psychopathy') likely represent more beneficial adaptions in general.[28] Psychopathic traits include a lower arousal threshold (less or no fear, desire for extreme stimulation, very low inhibition) and it is argued these improve mating success in men, whereas autism clearly is detrimental to mating success.[29]

In a similar vein, Overskied (2016) argued that many powerful politicians throughout recent history, such as as Angela Merkel, Lyndon B Johnson, and Nelson Mandela, among others, exhibited significant subclinical autistic traits, and the increase in male reproductive success associated with this status could explain some of the apparent rise in the prevalence of ASD in recent times. Overskied attempted to explain the discrepancy in the diagnosis of the disorder by sex by noting the reproductive success associated with high status is typically only found in men, with women's high status decreasing their reproductive success. He claims these subclinical autistic behaviors shared a common cause with actual autism, pre-natal testesterone exposure, in accordance with Baron-Cohen's extreme male brain theory. He also stated that the high cortisol levels often found in autistics may serve to inhibit the expression of such socially dominant behaviors in them, whereas the powerful figures he claimed exhibited sub-clinical autistic traits may not be subject to such high cortisol levels. [30]

Other theorists have examined autism through a life history framework, claiming that autism represents an extreme slow life history strategy (later age of reproduction, slower growth, focus on acquiring resources instead of early reproduction, and so on), with autistic traits perhaps being associated with the acquisition of specialized skills that may have served to enhance the eventual reproductive success of individuals that bore these traits in human's ancestral past. Some research has indeed indicated that autistic traits are associated with other traits that reflect a slow life history strategy, while schizotypic traits were found to possibly reflect a fast life history strategy.[31]

Relationship between ASD, physical masculinity, and looks[edit | edit source]

In apparent contrast with the extreme male brain theory, there is some research indicating those (male and female) are more physically androgynous then NTs, possibly contributing to the higher incidence of inceldom among autists. A study in the Journal of Neurodevelopmental Disorders demonstrated that males with higher levels of 'autistic traits' were generally more physically feminine then males with lower levels of autistic traits and vice versa for females. [32]

The authors hypothesise that it is possible that those with ASD have more androgynous physical appearance but more male brains in regards to systemising/empathising. However their findings are directly contradicted by another study using similar methodology, which found that pre-pubescent children with ASD were more facially masculine and those with more severe symptoms tended towards being the most masculinized, utilizing 3D face tracking software. [33]

One of the explanations given by the authors of second study are that the first study examined adults, while theirs studied children. It is possible (speculation) that the social victimisation and exclusion suffered by many autists results in higher levels of cortisol and the subsequent lowering of testosterone that results from high cortisol levels, leading to a higher Cortisol/T ratio, which may result in a incomplete level of masculization of the face and body during puberty. This would explain the lack of masculine traits, such as a strong mandible/square jaw, but not the hyper feminine traits such as large eyes and actually having a girls face. Other explanations the authors of the series of studies gave were possible methodological errors in the first study, and since autism is not a single concrete disorder and set of universal symptoms but a 'spectrum' of behaviours and neurological differences, there is the possibility that the autists higher in social deficits are the more masculinized ones, whereas those higher in systemising and obsessive interests are not.

In addition, there is evidence that those with ASD have less symmetrical faces than neurotypicals. For instance, a study in published in 2010 found evidence of "significant facial asymmetry" in boys with ASD, particularly in the supra and periorbital regions in front of the frontal pole of the right hemisphere of the brain.[34] This could be caused by differences in brain grown or/and genetic factors, since the mothers of those with ASD generally exhibited similar facial asymmetry. This could result in those with ASD being, on average, less attractive as compared to NTs, due to facial symmetry being generally found to be a component of facial beauty.[35]

In accordance with the blackpill there is also some evidence that the social difficulties that those with ASD face do not only originate with the neurological traits of the disorder, but also with how those with the disorder are perceived by others. An article in the scientific journal Nature,[36] presented a series of studies that demonstrated that when shown photos and clips of social interactions(filmed via first person with a go pro camera) of a group of ASD versus neurotypical individuals, ASD individuals were, as a group perceived as significantly less attractive, dominant, likeable, and fun to 'hang-out' with. They were however, perceived as roughly equally trustworthy, smart and good to live near compared to NT controls. Their findings also demonstrated that the "negative first impressions of adults with ASD occurred only when audio and/or visual information was present, and not when the transcript of their speech content was evaluated. This discrepancy suggests that social presentation style rather than the substantive content of social speech drove negative impression formation of individuals with ASD.

There are autistic male models, that literally look autistic but are still somehow objectively good looking at the same time.[37]

Relationship between ASD and behavioral androgyny[edit | edit source]

In seeming contradiction to the "extreme male brain" theory of the etiology of ASD, there is also some evidence that ASD is associated with behavioral androgyny in both sexes. However, as stated above, the theory does not claim that those with ASD are more "masculine" in a sense that accords with cultural/biological definitions of masculinity. Merely that exposure to excessive levels of androgens in the pre-natal environment is one of the main causes of the disorder, and that this androgen exposure is associated with traits that masculinize the brain of those with ASD in certain contexts, such as causing less empathy and/or a greater tendency toward systemizing (e.g. an extreme exaggeration of the general male tendency to be interested in "things" instead of "people"[38][39]).

Regarding the behavior profiles typical of those with ASD, a study published in 2014 found that, using a modified version of the Bem Sex Role Inventory, those with ASD generally exhibited a more androgynous gender profile,[40]. This was mainly based on those with ASD generally reporting having less of a competitive drive, poorer leadership abilities and lower assertiveness. However, women with ASD reported a greater masculinized gender identity, and two thirds stated they were tomboys in childhood vs one-third of control women.

Another study in 2010 found that those with ASD were 10 times more likely to be referred to a gender identity clinic than those in the general population.[41]. This poses a problem to the extreme male brain theory of autism, because both sexes were equally likely to exhibit gender dysphoria. Whereas one would expect females to be dysphoric than males if the extreme male brain theory was valid. However, the authors state that this form of gender dysphoria may be atypical, and could possibly be related to the obsessional interests often found in those in ASD.

It was also found that, contrary to the majority of typical developing individuals with gender dysphoria, those in the study who exhibited both gender dysphoria and ASD were not attracted to their natal sex, but were attracted to individuals of the opposite birth sex. This may also be explained by the Trans-vestigiality hypothesis, i.e. the idea that the social exclusion and sexual frustration often experienced by autistic males in particular, may contribute to them 'transitioning' to a female gender identity in order to gain access to women, by evading competition with other males. They possibly also romantically benefit from the social cachét that progressive circles often confer upon transsexuals.

Women on aspies[edit | edit source]

Even when those with Aspergers do manage to get into relationships with women, likely primarily due to some making good betabux providers due to having high-paying careers demanding specialist skills, there is some evidence that these relationships are fraught with tensions and often unstable.[42] A few choice quotes from disgruntled wives of men with Asperger's (also good evidence of female solipsism):

After 23 years of marriage to an AS husband who is a good provider and basically decent person, all I can say is “DON’T DO IT. Run, run, run as fast as you can. You may love this person, but unless you also despise yourself, you need to leave the relationship as far behind you as possible.”

And:

What do we do about aspie men? Do we just name and shame them on a website so other women can avoid? And what about the issue of being a man enough to confess you are an aspie, on the first or second date? Shouldn’t that be mandatory? This is a psych condition that badly hurts women like me, after all. I think we have a right to know.”

There is much more were that came from:

Aspergers men are a nightmare. I accidentally married someone with AS. And I stress ACCIDENTALLY, as I have seen the devastation that is “being” with one of these people. They should come with a warning and anyone displaying these behaviors should be tested in school so that us normal people don’t get trapped in something that ruins our lives. Yeah they’re all different yeah yeah, I know, some are worse than others. No one can be happy with these people. NO ONE. WHATSOEVER. Seriously. My life is devastated from one of these un-empathetic, desolate wasteland-of-emotions people. Learn to think like them? F*** that. That’s impossible and would require losing most of the characteristics that make us human, that allow us to connect to others.

Dating advice[edit | edit source]

There has been little research on what determines dating success among the few autists who have it. One study developed 3 key tips for autistic online daters:[43]

  • Be consistent in your online profile (attributes and interests).
  • Be explicit about your autism.
  • Frame your personality attributes and interests using positive wording

There is some evidence that autistic males may be more compatible with autistic females than with NT females (at least in the near-term that is):[44]

  • "Further, similar to speed-dating studies with typical adults, participants matched from speed-dating events led to electronic communication between couples, and dates for approximately one third of matches."
  • "the content of participants’ conversations felt formal to an outside observer"

References[edit | edit source]

  1. https://iancommunity.org/cs/simons_simplex_community/dsm5_and_asd
  2. https://icd.who.int/browse11/l-m/en#/http://id.who.int/icd/entity/120443468
  3. Die ‘Autistischen Psychopathen’ im Kindesalter, Archiv für Psychiatrie und Nervenkrankheiten (1944), 117, pp. 76-136 German:http://www.neurodiversity.com/library_asperger_1944.html English translation:https://psycnet.apa.org/record/1992-97284-002
  4. "The term psychopathy itself gained a specific and notorious meaning of a condition of amorality and anti-social or violent behaviour. Such a morally pejorative concept is said to have not been intended by Koch; he had applied the term 'psychopathic' to mean originating from an organic defect in the brain, and the term inferiority to simply refer to dysfunction. However, it was probably his concept and terminology that provided the unfortunate conglomeration of aspects of inferiority, amorality and socially harmful behavior."https://peoplepill.com/people/julius-ludwig-august-koch/
  5. https://www.nature.com/articles/d41586-018-05112-1
  6. https://www.psychologytoday.com/au/blog/my-life-aspergers/201303/how-much-aspergers-is-really-face-or-emotion-blindness
  7. https://www.researchgate.net/publication/262581068_Brief_Report_Parent-Child_Sexuality_Communication_and_Autism_Spectrum_Disorders
  8. Graham Holmes, Laura & Himle, Michael. (2014). Brief Report: Parent-Child Sexuality Communication and Autism Spectrum Disorders. Journal of autism and developmental disorders. 44. 10.1007/s10803-014-2146-2
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789215/
  10. https://link.springer.com/article/10.1007%2Fs10803-019-04101-1#aboutcontent
  11. Dickerson Mayes S, Gorman AA, Hillwig-Garcia J, Syed E. 2013. Suicide ideation and attempts in children with autism. Research in Autism Spectrum Disorders. 7(1): 109-119. https://www.sciencedirect.com/science/article/abs/pii/S1750946712000931
  12. Collingwood J. 2018. Suicidal Thoughts 10 Times More Likely in Adults With Asperger’s. PsychCentral. https://psychcentral.com/news/2014/10/13/suicidal-thoughts-10-times-more-likely-in-adults-with-aspergers/76016.html
  13. Hirvikowski T, Mittendorfer-Rutz E, Boman M, Larsson H. 2016. Premature mortality in autism spectrum disorder. The British Journal of Psychiatry. 208(3): 232-238. https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/premature-mortality-in-autism-spectrum-disorder/4C9260DB64DFC29AF945D32D1C15E8F2
  14. Cassidy S, Bradley P, Robinson J, Allison C, McHugh M, Baron-Cohen S. 2014. Suicidal ideation and suicide plans or attempts in adults with Asperger’s syndrome attending a specialist diagnostic clinic: a clinical cohort study. Lancet Psychiatry 1:142-147 https://www.thelancet.com/pdfs/journals/lanpsy/PIIS2215-0366(14)70248-2.pdf
  15. https://www.ncbi.nlm.nih.gov/pubmed/24888361?dopt=Abstract
  16. https://www.sciencedaily.com/releases/2019/07/190729094538.htm/
  17. https://www.psychologytoday.com/intl/blog/the-imprinted-brain/201506/testing-the-extreme-female-brain-theory-psychosis
  18. https://www.pnas.org/content/115/48/12152?fbclid=IwAR0ngaYIo88A77EKpALefnsr54ZZpPWGbatCYNPBcC84HgcDGmsZ2c6VgB4
  19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895441/
  20. https://www.who.int/news-room/fact-sheets/detail/autism-spectrum-disorders
  21. https://www.ncbi.nlm.nih.gov/pubmed/26401017/
  22. https://www.simonsfoundation.org/2015/07/27/autism-risk-genes-success-with-the-simplex-approach/
  23. https://www.sciencedirect.com/science/article/abs/pii/S1750946714002943
  24. https://www.sciencedirect.com/science/article/abs/pii/S0890856719301261
  25. https://www.ncbi.nlm.nih.gov/pubmed/24581740
  26. https://www.scientificamerican.com/article/females-are-genetically-protected-from-autism/
  27. https://www.academia.edu/36525083/ADHD_Autism_and_Psychopathy_as_Life_Strategies_The_Role_of_Risk_Tolerance_on_Evolutionary_Fitness
  28. https://www.reddit.com/r/BlackPillScience/comments/bnnr6r/teenage_boys_with_adhd_are_much_more_successful/
  29. https://link.springer.com/article/10.1007/s40806-019-00213-0
  30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005963/
  31. https://www.sciencedirect.com/science/article/abs/pii/S1090513814000580
  32. https://jneurodevdisorders.biomedcentral.com/articles/10.1186/s11689-015-9109-6
  33. https://www.nature.com/articles/s41598-017-09939-y#Sec17
  34. https://www.ncbi.nlm.nih.gov/pubmed/18317467
  35. https://www.annualreviews.org/article/suppl/10.1146/annurev.psych.57.102904.190208/suppl_file/ps.57.rhodes.appendix2.pdf
  36. https://www.nature.com/articles/srep40700
  37. https://www.kemifilani.ng/2019/06/indias-first-male-model-with-autism-is-making-headlines.html
  38. https://www.researchgate.net/publication/38061313_Men_and_Things_Women_and_People_A_Meta-Analysis_of_Sex_Differences_in_Interests
  39. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166361/
  40. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087961
  41. https://dx.doi.org/10.1007%2Fs10803-010-0935-9
  42. http://heartlessaspergers.com/
  43. https://www.sciencedirect.com/science/article/pii/S0747563219301566
  44. https://escholarship.org/uc/item/6kw0v3mf

See Also[edit | edit source]

Redpill

Game

GameNeggingSMVBeautyCharismaFashionBullyingLMSPUAAssholeTalk therapyIOIDominance hierarchyIODSocial circleSlayerN.L.P

Personality

CoolCharismaStoicAssholeNice guyAnxiousConfidentAsperger's SyndromeIQRationality

Pick Up Artists

Ross Jeffriesr/TRPReal Social DynamicsRooshVOwen CookPlayer SupremeWinston WuList of fraudulent people in the seduction community

Sexuality

HypergamyCasual sexPump and dumpRapeBetabuxReproductive successSex driveBateman's principleSexual conflictFeminine imperativeAdverse effects of inceldomMaslow's hierarchy of needsHomosexualityHomocel hypothesisDemographics of inceldomPolygynyPolyandryMonogamyFisherian runaway

Other theories

Timeless quotes on womenFemales are socially ineptWomen-are-wonderful effectGynocentrismPolitical correctness‎Virtue signalingApex fallacyClown worldFeminismSexual revolutionFemale hypoagencyFemale solipsismFemme fataleBriffault's lawHalo effectAntifragilityTriggeredScientific BlackpillScientific Blackpill (Supplemental)