Outbreeding depression is a stark decrease in an organism's ability to survive and reproduce due to an extreme regression toward the mean. Generating intermediate genotypes that are less fit than either parent as well as a breakdown of biochemical or physiological compatibility. For example, selection in one population might favor a large body size, whereas in another population small body size might be more advantageous, while individuals with intermediate body sizes are comparatively disadvantaged in both populations.https://en.wikipedia.org/wiki/Outbreeding_depressi
Mixed race black and white couples face higher odds of prematurity and low birth weight.  Infants born to biracial parents (mother and father from either Black or White races) also experience higher adverse birth outcomes. 
Outbreeding depression checklist
- Are you noticeably mixed race?
If not great.
- If so have you and your family been noticeably mixed race for less than 3 generations?
- Are you and or your family hyperactive?
- Do you and or your family love to travel out of the country?
- Are you extremely average looking, meaning people always come up to you and tell you, you "look" like so and so, or mistake you for someone else?
The more "yes" answers to these questions the more likely a person currently is in the midst of an outbreeding depression.
- Stanford Medicine (2008). Asian-white couples face distinct pregnancy risks, Stanford/Packard study finds
- Sun Young Yang, Un Suk Jung, and Geum Joon Cho (2017). Analysis of Pregnancy Outcomes among Interracial Couples in Korea
- Zosia Bielski (2008). Asian mom, white dad: C-section more likely
- American Journal of Obstetrics and Gynecology (2008). Perinatal outcomes among Asian–white interracial couples
- Journal of Women's Health (2010). Prematurity and Low Birth Weight as Potential Mediators of Higher Stillbirth Risk in Mixed Black/White Race Couples
- Srinivasjois RM, et al. Acta Obstet Gynecol Scand. 2012. Biracial couples and adverse birth outcomes: a systematic review and meta-analyses.